
Introduction
Saffron (Crocus sativus) is gaining recognition beyond kitchen and cosmetic uses—it shows promise in mental health care.
Clinical Evidence
Multiple studies confirm saffron’s effectiveness in reducing symptoms of mild to moderate depression and anxiety. In some trials, daily supplementation (30–60 mg) delivered benefits comparable to standard antidepressants like sertraline and fluoxetine, with fewer side effects. Other trials also report improvements in mood, social functioning, and overall quality of life.
The bioactive compounds in saffron—crocin, crocetin, and safranal—are believed to act as antioxidants and modulators of neurotransmitters like serotonin, which may underlie its mood‑enhancing properties.
Safety & Considerations
Saffron is generally well‑tolerated, but high doses can be toxic. Mild side effects such as nausea or dry mouth have been reported. Due to variability in supplement quality, using third‑party tested products is recommended, and consultation with a medical professional is advised before use.
Conclusion
With growing evidence, saffron is emerging as a natural adjunct in managing mild to moderate mental health conditions, offering a safe and culturally rooted alternative in psychiatric care.
